This concise professional reference provides a fundamental framework for the design and operation of solidstate fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes. Bioreactors in solid state fermentation technology. It was c sidered for the production of enzymes in the early. The previous chapters have presented solidstate fermentation ssf bioreactors that operate in batch mode. Design aspects of solid state fermentation as applied to microbial. Efficiency of developed solid state bioreactor ukm. Design aspects of bioreactors for solidstate fermentation.
In recent years, substantial credibility in employing solidstate fermentation ssf technique has been witnessed owing to its numerous advantages over submerged fermentation smf. Solidstate fermentation ssf is defined as a fermentation process during which microorganisms grow on the surface andor interior of a solid matrix without a freeflowing aqueous phase. Pdf solidstate fermentation bioreactor fundamentals. These include 1 the araucaria foundation fundacao araucaria, a research agency of the state of parana. Solidstate fermentation bioreactors and fundamentals. Since my move to brazil, i have received funding from several state and federal granting bodies. Fundamentals of design and operation this concise professional reference provides a fundamental. Abstract background the growth of aspergillus awamori and aspergillus oryzae in a selfdesigned, multistacked circular tray solidstate bioreactor ssb, operating in solidstate fermentation.
Design aspects of solid state fermentation as applied to. In spite of enormous advantages, true potential of ssf technology has not been fully realized at industrial scale. Although solidstate fermentation ssf has been practiced for many centuries in the preparation of traditional fermented foods, its application to newer products within the framework of modern biotechnology is relatively restricted. Although batch operation is the most common type of operation in ssf processes to date, it is also possible to design and operate continuous ssf bioreactors. In a broader definition, ssf can include processes with a liquid phase at maximal substrate concentrations or on inert carriers 1. Development of fundamental aspects of ssf, bioprocess and products. Solidstate fermentation bioreactors fundamentals of. Solidstate fermentation ssf has advantages, such as lower water use and higher volumetric productivity, over those of submerged fermentation. Fermsostat is a developed laboratory scale solid state fermenter. Solidstate fermentation bioreactors fundamentals of design and. Ssf bioreactor design should carefully consider design and operating variables, especially aeration transfer, temperature control including. Solid state fermentation ssf has been practiced for centuries in.